Co-expression of CDX2 and MUC2 in gastric carcinomas: Correlations with clinico-pathological parameters and prognosis
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چکیده
منابع مشابه
p16, cyclin D1 and Rb expression in colorectal carcinomas: Correlations with clinico-pathological parameters and prognosis.
In an immunohistochemical study, 200 colorectal carcinomas were stained with monoclonal antibodies recognizing the cell cycle regulators p16, cyclin D1 and Rb, in order to study their expression and prognostic impact. Cyclin D1 and Rb were generally expressed in a nuclear pattern, whereas p16 also exhibited cytoplasmic reactivity. Immunoreactivity was observed in 94% (p16), 75% (cyclin D1) or 9...
متن کاملExpression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients.
Our previous immunohistochemical studies for the expression of MUC1 mucin antigen (which was detected by monoclonal antibody DF3) and MUC2 mucin antigen (which was detected by polyclonal antibody anti-MRP) in pancreatic and intrahepatic bile duct tumors demonstrated that invasive carcinoma with poor outcome showed a pattern of MUC1+ and MUC2- expression, whereas many of the noninvasive tumors w...
متن کاملCDX2 and MUC2 protein expression in extrahepatic bile duct carcinoma.
Although CDX2-mediated intestinal metaplasia and its association with gastric and esophageal carcinoma have been well described, its function in extrahepatic bile duct (EBD) carcinoma remains unclear. CDX2 and MUC2 expression were examined in 193 EBD carcinomas, and observed in 37.3% and 42.0%, respectively. Both CDX2 and MUC2 were observed in 27.4%. CDX2 (P<.001) and MUC2 (P<.001) were correla...
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15 صفحه اولThe expression of hTR and hTERT in human breast cancer: correlation with clinico-pathological parameters
BACKGROUND Telomerase is a ribonucleoprotein enzyme that synthesizes telomeres after cell division and maintains chromosomal stability leading to cellular immortalization. Telomerase has been associated with negative prognostic indicators in some studies. The present study aims to detect any association between telomerase sub-units: hTERT and hTR and the prognostic indicators including tumour's...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2005
ISSN: 1007-9327
DOI: 10.3748/wjg.v11.i21.3182